Evidence Review and Synthesis

Evidence review and synthesis is the systematic identification, appraisal and aggregation of published research on a defined clinical or economic question. It provides the evidential foundation on which health economic models, health technology assessment (HTA) submissions and market access strategies are built.

The rigour with which evidence is reviewed determines the credibility of everything that follows. A health economic model is only as reliable as the clinical inputs behind it and an HTA submission is only as persuasive as the evidence base it rests upon. Review methodologies span a broad spectrum — from rapid and scoping reviews conducted to inform early-stage decisions under tight timelines, through to full systematic reviews with meta-analyses conducted to formal protocols and reported in accordance with scientific standards. Selecting the appropriate review type for a given decision, then executing it to the appropriate standard, requires both methodological expertise and a clear understanding of how the findings will ultimately be used.

I conduct a variety of reviews, both common and specialised, to answer clinical and economic research questions. My commissioned and published work has required mastery of pairwise and proportional meta-analyses, and of mixed treatment comparisons — enabling me to deliver rigorous and comprehensive summaries for clients and decision-makers.